Special Blue Mutagens are helpful to magically inclined players in The Witcher 3. Each Special Blue Mutagen will provide a +5% to Sign Intensity. They will also provide an additional +5% for every blue ability they’re attached to for a max bonus of +20%.

For players wanting that appealing +20% Sign intensity bonus it’s recommended to farm various monsters to obtain these Mutagens. There are a few monsters in the world, some far more challenging than others to take down and some being a great source of limitless Mutagens.

9 Ancient Leshen Mutagen

Ancient Leshens are a source of Special Blue Mutagens and are a fearsome enemy to face. They appear in Velen and Skellige with the most reliable being the Abandoned Sawmill quest. Unless the player is desperate or ambitious these aren’t recommended creatures to farm for their Ancient Leshen Mutagen.

If the player does fight one it helps to have Relict Oil and Dimeritium Bombs. Fire seems to be an effective tool when fighting these creatures. It’s also important to note that the player will never fight a lone Leshen. It will always have a swarm of crows, wolves, and other creatures to fight alongside them.

8 Basilisk Mutagen

Basilisks can drop the Basilisk Mutagen when defeated. The good news is that Basilisk are guaranteed to drop the Special Blue Mutagen, the bad news is there are no Contracts for them making them tough to find. One can usually be found guarding a treasure on an island by the Lighthouse of Novigrad. The quests Ciri’s Story: Out of the Shadows and Dowry will also feature these beasts.

Basilisks possess potent venom making it highly recommended to use Golden Oriole when battling them. Grapeshot is also handy for knocking them out of the sky. Draconid Oil for the weapons and using Aard signs are the way to go when fighting these beasts.

7 Chort Mutagen

Chorts will drop Chort Mutagens when defeated. They appear in Velen, Skellige, and Kaer Morhen. They can be encountered in the Contract Mysterious Tracks and the quest Berengar’s Blade. This can make them a viable source for unlimited Special Blue Mutagens.

Chorts are strong and incredibly fast. They’re go to attack is to charge at high speeds towards opponents. Then when their foe is knocked to the ground they bite, scratch, and pummel their victims to death. The key is to avoid this charge and attack them while they’re stunned after smashing into something. Relict Oil and Devil’s Puffballs make the fight a bit easier.

6 Cockatrice Mutagen

Cockatrices are a rare source of Special Blue Mutagens. Cockatrices will respawn near Arette and one nonspawning version can be found by the lake near Fornhala. The best method for farming this Mutagen is through the Contract Shrieker which has a weaker named variant.

These winged beasts are very annoying to fight. Grapeshot while they’re in the air will help. One the ground using Draconoid Oil and Aard will go a long ways. Swallow Potions to negate the bleed effect of their attacks is also helpful.

5 Earth Elemental Mutagen

Earth Elementals are a tough creature to obtain Special Blue Mutagens from. They are found in Elven Ruins and one is guarding a treasure north of the House of Respite. The quests The King is Dead -Long Live the King and The Witcher’s Forge features these brutes.

These constructs can take a surprisingly amount of damage making it very common for swords to break during combat. Elementa Oil to milk extra damage out of those swords and Dimeritium bombs go a long way to making the fight a shorter one. Ultimately the player needs to be patient and swing away.

4 Ekhidna Mutagen

Ekhidna are a tricky monster to farm for their Ekhidna Miutagens because they’re water based. Meaning most of the time they won’t drop anything in the water. The key is to hunt Ekidhna on land like those west of Skellig by the Tower Outta Nowheres. One will also show up during Here Comes the Groom Contract.

Grapeshot is recommended to drop them out of the sky, the player just needs to make sure they land on solid ground. Once felled using Hybrid Oil and a combination of Igni and Aard signs will help put them down for good. Ekhidna are fantastic to farm thanks to the abundance of loot they drop, assuming they’re on land.

3 Foglet Mutagen

Foglets are fantastic for farming Special Blue Mutagens as any one will drop one, albeit the drop rate is low. They appear wherever fog is and the quests The Isle of Mists, The Final Trial, and Echoes of the Past have guaranteed encounters. The best way to farm them is through the Contract Swamp Thing.

Foglets can be really tricky or really easy encounters depending on the player’s timing and level. A single Aard Sweep can insta-kill a Foglet if it’s visible. Otherwise the player needs to use Signs or bombs to make them visible before going in for the kill.

2 Forktail Mutagen

Forktails are yet another flying beast that can be hunted for Forktail Special Blue Mutagens. They can be found flying in Velen, Skellige, and White Orchard. The best sources are the quests To Bait a Forktail…, Scavenger Hunt for Griffin School Gear, and the Contract Dragon.

Grapeshot as always is great for dropping a winged creature to the ground. Golden Oriole will counteract the worst of the Forktail’s poison. Draconid Oil gives weapons more punch and Aard helps immensely. These are also a great source of Dragon Scales.

1 Leshen Mutagen

Leshens are a source of the Leshen Mutagen. While not as dangerous as Ancient Leshens they still pose a threat to the player. A Leshen can be found northwest of the Aeramas’ Abandoned Manor. The stronger Kernun can be found during the Contract Lord of the Wood.

The same tactics for fighting Ancient Leshens apply here. Relict Oil to strengthen weapons and Dimeritium Bombs to apply burn. Igni signs help a lot. It’s also important to not get swarmed by the animal minions and keep tabs on the nightmare while it moves around in smoke form.

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